Immunity against helminthic infections
Parasitic Infections Impact Millions cancer testicular metastasis retroperitoneal Helminth- induced immunity Conținutul Translation of "raspunsul imunitar" in English Immunity against helminthic infections Comentarii The type 2 immune response that develops immunity against helminthic infections infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified.
It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL, is associated with helminth infections in both humans and mice.
This response is complex and includes effector functions that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. But just as importantly, helminth- induced immunity type 2 immune response can also mediate tolerance mechanisms, which can mitigate helminth- induced immunity injury as these large multicellular parasites transit through vital organs.
The tolerance mechanisms include both tissue repair and immune regulatory effects. Immune Immunity against helminthic infections against Parasitic Infections These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be mined for the development of novel immunotherapies that may enhance wound healing, control of autoimmune immunity against helminthic infections inflammatory diseases and regulation of metabolic homeostasis.
In this book, leading researchers in this exciting helminth- induced immunity dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation. An aparitie: 26 Dec Autor: William C.